A very talented colleague of mine here in the UK has recently completed an online tutorial (along with a video) on how to set up your Wacom Cintiq Companion pen tablet for optimised use in Zbrush.
For those who do not know, Zbrush specialists are particularly fond of switching over from using a mouse to a pen tablet, as it allows for the most freedom of movement and pressure sensitivity when performing surface sculpture.
Have a look at what he’s come up with: